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Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.
apoptosis-related cysteine protease; Casp11; CASP-11; CASP13; CASP-13; CASP4; CASP-4; caspase 11; caspase 4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; caspase 4, isoform alpha, small subunit; Caspase-11; Caspase-13; Caspase-13 subunit 1; Caspase-13 subunit 2; caspase-13A; caspase-13B; caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-4 subunit p20; Caspl; ERICE; Evolutionary related interleukin-1-beta-converting enzyme; Ich3; ich-3; MGC137679; Protease ICH-3
100 µg